陈洋博士个人简介

【教师简介】

      陈洋，理学博士，合乐注册HL8副教授，硕士研究生导师，主要从事具有重要生理活性天然产物的分子构建、结构多样性改造、药理活性及作用机制研究，以及药物开发应用基础研究。相关研究工作已获多项基金项目支持，近年来以第一作者或通讯作者已发表学术论文20余篇，授权专利2件。

邮箱：ychen1@gzu.edu.cn

【主持项目】

1.   国家自然科学基金面上项目，主持

2.   国家重点研发计划子课题，主持

3.   贵州省自然科学基金面上项目，主持

【近三年学术论文】

1. Chen, Y.*; Zuo, M.; Wu, T.; Huang, J. Diels-Alder Reaction Towards the Synthesis of Cephanolide A: Construction of the A/B/C/D Ring System, X-ray, DFT, and Antibacterial Activity. J. Mol. Struct., 2025, 1339, 142473 (1-18).

2. Zuo, M.; Chen, Y.*; Zhao, H.; Wu, T.; He, S.; Huang, J.* Synthesis, X-ray, DFT and antibacterial activity of a novel 1-indanone derivative. J. Mol. Struct., 2025, 1339, 142422 (1-16).

3. Long, A.; Li, D.; Yan, B.; Yuan, Y.; Liu, H.; Yang, L.; Chen, Y.*; He, S.*, General one-step access to unsymmetric propargylic acetals via alcohol functionalization with allenyl ethers. RSC Adv., 2025,15, 11770-11773.

4. Qu, H.; Dai, L.; Guo, Z.; Wang, J.; Zhang, X.; Chen, W.; Chen, Y., Antifungal activity of dimethyl trisulfide and potential biocontrol against Alternaria alternata on postharvest Lycium barbarum. Eur. J. Plant Pathol.,2025,171, 645-660.

5. Liu, Q.; Zuo, M.; Song, Y.; He, S.; Huang, J.;Chen, Y.*. Bioinspired total synthesis and biological activity of pegaharine A. Pest Manag. Sci., 2024, 80, 1372-1381.

6. Que, Y.; Lei, W.; Fang, Y.; He, S.*; Chen, Y.*, Recent advances in (4 + 3) cycloaddition of allenes. Green Synth. Catal.2024, 5, 270–276.

7. Li, M.; Chen, P.; Liu, H.; Huang, J.*; Chen, Y.*. Review of the total synthesis of the aromatic abietane diterpenoid ferruginol. Synthesis-Stuttgart 2024, 56, 1355-1368.

8. Ai, L.; Fu, S.; Li, Y.; Zuo, M.; Huang, W.; Huang, J.; Jin, Z.; Chen, Y.*, Natural products-based: Synthesis and antifungal activity evaluation of novel L-pyroglutamic acid analogues. Front. Plant Sci. 2022,13, 1102411.

9. Lei, W.; Song, Y.; Long, A.; Que, Y.; He, S.*; Zhong, H.*; Chen, Y.*, Stereoselective (4 + 3) cycloadditions of allenyl ethers-furans by chiral auxiliaries inducing and evaluation of anti-breast cancer activity. Front. Plant Sci. 2022,13, 1087899.

10. Zhao, H.; Pan, H.; Yao, Y.; Huang, J.*; Chen, Y.*, Recent advances in the total synthesis of cephalotane-type norditerpenoids from Cephalotaxus sinensis. Synthesis-Stuttgart 2022,54, 3317-3327.

【授权专利】

1. Preparation of sex attractant for Phthorimaea operculella. CN115490589

2. Method for preparing 4-chloroindole-3-acetic acid using trifluoroacetic acid. CN114573496